Article
Striatal Nurr1, but not FosB expression links a levodopa-induced dyskinesia phenotype to genotype in Fisher 344 vs. Lewis hemiparkinsonian rats.
Experimental neurology - 1 Aug 2020
Steece-Collier Kathy, Collier Timothy J, Lipton Jack W, Stancati Jennifer A, Winn Mary E, Cole-Strauss Allyson, Sellnow Rhyomi, Conti Melissa M, Mercado Natosha M, Nillni Eduardo A, Sortwell Caryl E, Manfredsson Fredric P, Bishop Christopher
Abstract excerpt
Numerous genes, and alterations in their expression, have been identified as risk factors for developing levodopa-induced dyskinesia (LID). However, our understanding of the complexities of molecular changes remains insufficient for development of clinical treatment. In the current study we used gene array, in situ hybridization, immunohistochemistry, and microdialysis to provide a unique compare and contrast...
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