Article
HIV-1 Exploits CLASP2 To Induce Microtubule Stabilization and Facilitate Virus Trafficking to the Nucleus.
Journal of virology - 1 Jul 2020
Mitra Sahana, Shanmugapriya Shanmugapriya, Santos da Silva Eveline, Naghavi Mojgan H
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) exploits a number of specialized microtubule (MT) plus-end tracking proteins (commonly known as +TIPs) to induce the formation of stable microtubules soon after virus entry and promote early stages of infection. However, given their functional diversity, the nature of the +TIPs involved and how they facilitate HIV-1 infection remains poorly understood. Here, we identify...
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