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Cellular mitophagy: Mechanism, roles in diseases and small molecule pharmacological regulation

1 Jan 2023

Abstract excerpt

Cellular mitophagy means that cells selectively wrap and degrade damaged mitochondria through an autophagy mechanism, thus maintaining mitochondria and intracellular homeostasis. In recent years, mitophagy has received increasing attention as a research hotspot related to the pathogenesis of clinical diseases, such as neurodegenerative diseases, cardiovascular diseases, cancer, metabolic diseases, and so on. It...

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PMID: 36632220
DOI: 10.7150/thno.79876

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