Article
Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion.
Scientific reports - 4 May 2020
Frausto Ricardo F, Swamy Vinay S, Peh Gary S L, Boere Payton M, Hanser E Maryam, Chung Doug D, George Benjamin L, Morselli Marco, Kao Liyo, Azimov Rustam, Wu Jessica, Pellegrini Matteo, Kurtz Ira, Mehta Jodhbir S, Aldave Anthony J
Abstract excerpt
The advent of cell culture-based methods for the establishment and expansion of human corneal endothelial cells (CEnC) has provided a source of transplantable corneal endothelium, with a significant potential to challenge the one donor-one recipient paradigm. However, concerns over cell identity remain, and a comprehensive characterization of the cultured CEnC across serial passages has not been performed. To...
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