PNPLA3 Gene Polymorphism and Liver- and Extrahepatic Cancer-Related Mortality in the United States.

doi:10.1016/j.cgh.2020.04.058

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Article

PNPLA3 Gene Polymorphism and Liver- and Extrahepatic Cancer-Related Mortality in the United States.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 May 2021

Wijarnpreecha Karn, Scribani Melissa, Raymond Pascale, Harnois Denise M, Keaveny Andrew P, Ahmed Aijaz, Kim Donghee

Abstract excerpt

The palatin-like phospholipase domain-containing 3 (PNPLA3) rs738409 G allele is associated with nonalcoholic fatty liver disease (NAFLD), hepatocellular carcinoma,1 and all-cause or cardiovascular mortality in the general population.2 One recent Italian study reported an association between PNPLA3 polymorphism and liver-related events and mortality in biopsy-confirmed NAFLD.3 Regarding extrahepatic...

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Identifiers

PMID: 32360822
DOI: 10.1016/j.cgh.2020.04.058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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