Article
Impact of forced vital capacity loss on survival after the onset of chronic lung allograft dysfunction.
American journal of respiratory and critical care medicine - 15 Jan 2014
Todd Jamie L, Jain Rahil, Pavlisko Elizabeth N, Finlen Copeland C Ashley, Reynolds John M, Snyder Laurie D, Palmer Scott M
Abstract excerpt
RATIONALE: Emerging evidence suggests a restrictive phenotype of chronic lung allograft dysfunction (CLAD) exists; however, the optimal approach to its diagnosis and clinical significance is uncertain. OBJECTIVES: To evaluate the hypothesis that spirometric indices more suggestive of a restrictive ventilatory defect, such as loss of FVC, identify patients with distinct clinical, radiographic, and pathologic...
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