Article
Association of Genetic Polymorphisms of TGF-β1, HMOX1, and APOL1 With CKD in Nigerian Patients With and Without HIV.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jul 2020
Ekrikpo Udeme E, Mnika Khuthala, Effa Emmanuel E, Ajayi Samuel O, Okwuonu Chimezie, Waziri Bala, Bello Aminu, Dandara Collet, Kengne Andre P, Wonkam Ambroise, Okpechi Ikechi
Abstract excerpt
RATIONALE & OBJECTIVE: Recent studies in the human immunodeficiency virus (HIV)-infected population have suggested that there are genetic predispositions to the development of chronic kidney disease (CKD) in this context. We investigated the association of genetic polymorphisms of the genes encoding apolipoprotein L1 (APOL1), transforming growth factor β1 (TGF-β1; a profibrotic cytokine), and heme oxygenase 1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
