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Article

Crypt residing bacteria and proximal colonic carcinogenesis in a mouse model of Lynch syndrome

30 Apr 2020

Abstract excerpt

Abstract Colorectal cancer is a multifactorial disease involving inherited DNA mutations, environmental factors, gut inflammation and intestinal microbiota. Certain germline mutations within the DNA mismatch repair system are associated with Lynch syndrome tumors including right‐sided colorectal cancer with mucinous phenotype and presence of an inflammatory infiltrate. Such tumors are more often associated with...

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Identifiers

PMID: 32350866
DOI: 10.1002/ijc.33028

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