Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of genetic factors associated with fatty liver disease-related hepatocellular carcinoma.

Cancer medicine - 1 Sept 2023

Kogiso Tomomi, Ogasawara Yuri, Horiuchi Kentaro, Taniai Makiko, Tokushige Katsutoshi

Abstract excerpt

AIM: Single-nucleotide polymorphisms (SNPs) in PNPLA3 and hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) genes are associated with fatty liver disease (FLD) progression and carcinogenesis. In the present study, we evaluated the characteristics of Japanese FLD patients according to HSD17B13 polymorphisms. METHODS: We enrolled 402 patients who were clinically and pathologically diagnosed with FLD (alcoholic: 63...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GC gene

Share to PNPLA3 gene

Share to Genetic Predisposition to Disease

Share to Liver Neoplasms

Share to Non-alcoholic Fatty Liver Disease

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 37644826
DOI: 10.1002/cam4.6410
PMCID: PMC10524060

Genes

HSD17B13
PNPLA3
GC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of genetic factors associated with fatty liver disease-related hepatocellular carcinoma.PMID 37644826Read ↗

Advances in the genetics of nonalcoholic fatty liver disease.Semantic proximity Read ↗

Outcomes of Japanese patients with non-alcoholic fatty liver disease according to genetic background and lifestyle-related diseases.Semantic proximity Read ↗

Relevance of PNPLA3, TM6SF2, HSD17B13, and GCKR Variants to MASLD Severity in an Egyptian Population.Semantic proximity Read ↗

Update on genetics and epigenetics in metabolic associated fatty liver diseaseSemantic proximity Read ↗

Genetic variants associated with metabolic dysfunction-associated fatty liver disease in western China.Semantic proximity Read ↗

Is HSD17B13 Genetic Variant a Protector for Liver Dysfunction? Future Perspective as a Potential Therapeutic TargetSemantic proximity Read ↗

Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review.Semantic proximity Read ↗

Attenuated effect of PNPLA3 on hepatic fibrosis by HSD17B13 in Japanese patients with non-alcoholic fatty liver disease.Semantic proximity Read ↗

Genetic Contribution to Non-alcoholic Fatty Liver Disease and Prognostic Implications.Semantic proximity Read ↗

Leveraging Human Genetics to Identify Potential New Treatments for Fatty Liver Disease.Semantic proximity Read ↗

Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk scores.Semantic proximity Read ↗

Risk Factors of Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-AnalysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.