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Article

GM13133 is a negative regulator in mouse white adipocytes differentiation and drives the characteristics of brown adipocytes.

Journal of cellular physiology - 1 Jan 2018

You LiangHui, Zhou YaHui, Cui XianWei, Wang XingYun, Sun YaZhou, Gao Yao, Wang Xing, Wen Juan, Xie Kaipeng, Tang RanRan, Ji ChenBo, Guo XiRong

Abstract excerpt

Obesity is tightly associated with the disturbance of white adipose tissue storing excess energy. Thermogenic adipocytes (brown and beige) exert a critical role of oxidizing nutrients at the high rates through non-shivering thermogenesis. The recruitment of brown characteristics in white adipocytes, termed browning, has been considered as a promising strategy for treating obesity and associated metabolic...

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PMID: 28247947
DOI: 10.1002/jcp.25878

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