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Article

miR-30 Promotes Thermogenesis and the Development of Beige Fat by Targeting RIP140

9 Jan 2015

Abstract excerpt

Members of the microRNA (miR)-30 family have been reported to promote adipogenesis and inhibit osteogenesis, yet their role in the regulation of thermogenesis remains unknown. In this study, we show that miR-30b/c concentrations are greatly increased during adipocyte differentiation and are stimulated by cold exposure or the β-adrenergic receptor activator. Overexpression and knockdown of miR-30b and -30c induced...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 25576051
DOI: 10.2337/db14-1117

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