Article
Triple positive breast cancer: a distinct subtype?
Cancer treatment reviews - 1 Feb 2015
Vici Patrizia, Pizzuti Laura, Natoli Clara, Gamucci Teresa, Di Lauro Luigi, Barba Maddalena, Sergi Domenico, Botti Claudio, Michelotti Andrea, Moscetti Luca, Mariani Luciano, Izzo Fiorentino, D'Onofrio Loretta, Sperduti Isabella, Conti Francesca, Rossi Valentina, Cassano Alessandra, Maugeri-Saccà Marcello, Mottolese Marcella, Marchetti Paolo
Abstract excerpt
Breast cancer is a heterogeneous disease, and within the HER-2 positive subtype this is highly exemplified by the presence of substantial phenotypical and clinical heterogeneity, mostly related to hormonal receptor (HR) expression. It is well known how HER-2 positivity is commonly associated with a more aggressive tumor phenotype and decreased overall survival and, moreover, with a reduced benefit from endocrine...
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