Article
The natural course of pregnancies in women with primary atypical haemolytic uraemic syndrome and asymptomatic relatives.
British journal of haematology - 1 Aug 2020
Timmermans Sjoerd A M E G, Werion Alexis, Spaanderman Marc E A, Reutelingsperger Chris P, Damoiseaux Jan G M C, Morelle Johann, van Paassen Pieter
Abstract excerpt
Pregnancy has been linked to various microangiopathies, including primary atypical haemolytic uraemic syndrome (aHUS). Complement dysregulation, often linked to rare variants in complement genes, is key for primary aHUS to manifest and may play a role in pregnancy complications of the mother and fetus. The burden of such complications is unknown, making counselling of women with primary aHUS and asymptomatic...
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