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Article

Molecular Features of the Serrated Pathway to Colorectal Cancer: Current Knowledge and Future Directions.

Gut and liver - 15 Jan 2021

Satorres Carla, García-Campos María, Bustamante-Balén Marco

Abstract excerpt

Serrated lesions are the precursor lesions of a new model of colorectal carcinogenesis. From a molecular standpoint, the serrated pathway is thought to be responsible for up to 30% of all colorectal cancer cases. The three major processes of this molecular mechanism are alterations in the mitogen-activated protein kinase pathway, production of the CpG island methylation phenotype, and generation of microsatellite...

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Identifiers

PMID: 32340435
DOI: 10.5009/gnl19402
PMCID: PMC7817929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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