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Article

XRCC1 Gene Polymorphism Increases the Risk of Hepatocellular Carcinoma in Egyptian Population.

Asian Pacific journal of cancer prevention : APJCP - 1 Apr 2020

Naguib Mary, Helwa Mohamed M, Soliman Mohammed M, Abdel-Samiee Mohamed, Eljaky Ashraf M, Hammam Osama, Zaghla Hassan, Abdelsameea Eman

Abstract excerpt

Several major risk factors for hepatocellular carcinoma (HCC) have been identified, including chronic infection of hepatitis B virus (HBV) and hepatitis C virus (HCV). Nevertheless, only a fraction of infected patients develops HCC during their lifetime suggesting that genetic factors might modulate HCC development. X-ray repair cross complementing group1 (XRCC1) participates in the repair pathways of DNA. AIM:...

Topics

Adult
Biomarkers, Tumor
Carcinoma, Hepatocellular
Case-Control Studies
Egypt
Female
Follow-Up Studies
Genetic Association Studies
Genotype
Humans
Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Polymorphism, Single Nucleotide

Prognosis

X-ray Repair Cross Complementing Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 32334466
DOI: 10.31557/APJCP.2020.21.4.1031
PMCID: PMC7445958

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32334466-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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