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Article

The Evolving AML Genomic Landscape: Therapeutic Implications.

Current cancer drug targets - 1 Jan 2020

Horibata Sachi, Alyateem George, DeStefano Christin B, Gottesman Michael M

Abstract excerpt

Improved understanding of the genomic and molecular landscape of acute myeloid leukemia (AML) has resulted in a significant evolution of our understanding of AML biology and allows refined prognostication for those receiving standard combination chemotherapy induction. This dramatic increase in knowledge preceded, and was somewhat responsible for, at least some of eight new FDA drug approvals for AML. This review...

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Topics

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Share to Antibodies, Monoclonal, Humanized
Share to Antimetabolites, Antineoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antineoplastic Agents, Immunological

Share to Drug Approval

Share to Genomics

Share to Leukemia, Myeloid, Acute

Share to Protein Kinase Inhibitors

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Source

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Identifiers

PMID: 32329691
DOI: 10.2174/1568009620666200424150321
PMCID: PMC7442715

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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