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Article

An EDTA-resistant pyrazinamidase from non-pathogen Pseudonocardia carboxydivorans.

Biotechnology letters - 1 Sept 2020

Yan Chuang, Zhang Jingxuan, Wu Pan, Gan Yong, Zhang Guimin

Abstract excerpt

OBJECTIVES: To characterize a pyrazinamidase from non-pathogen Pseudonocardia carboxydivorans. RESULTS: A pyrazinamidase gene pncA encoding a 23-kDa protein PncA-Pse from P. carboxydivorans was over-expressed in Escherichia coli and characterized. This PncA-Pse can convert both pyrazinamide and nicotinamide efficiently with the optimal pH and temperature of pH 8.5 and 45 °C, respectively. Although ferrous iron...

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PMID: 32323078
DOI: 10.1007/s10529-020-02890-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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