Genetic polymorphisms of proteasome subunit genes of the MHC-I antigen-presenting system are associated with cervical cancer in a Chinese Han population.

doi:10.1016/j.humimm.2020.07.002

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Genetic polymorphisms of proteasome subunit genes of the MHC-I antigen-presenting system are associated with cervical cancer in a Chinese Han population.

Human immunology - 1 Aug 2020

Li Chuanyin, Dai Shuying, Yan Zhiling, Zhang Xinwen, Liu Shuyuan, Wang Xia, Wang Jun, Shi Li, Yao Yufeng

Abstract excerpt

Proteasome subunit beta types 8 and 9 (PSMB8, PSMB9) play critical roles in the human leukocyte antigen class I (HLA I)-presenting system. Studies have suggested that polymorphisms in the PSMB8 and PSMB9 genes may influence the immune functions of PSMB8 and PSMB9, and thus be associated with various human cancers. We investigated associations involving single nucleotide polymorphisms (SNPs) rs2071543 in PSMB8,...

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PMID: 32684411
DOI: 10.1016/j.humimm.2020.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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