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Article

A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.

Developmental cell - 20 Apr 2020

Puri Claudia, Manni Marco M, Vicinanza Mariella, Hilcenko Christine, Zhu Ye, Runwal Gautam, Stamatakou Eleanna, Menzies Fiona M, Mamchaoui Kamel, Bitoun Marc, Rubinsztein David C

Abstract excerpt

Autophagy involves engulfment of cytoplasmic contents by double-membraned autophagosomes, which ultimately fuse with lysosomes to enable degradation of their substrates. We recently proposed that the tubular-vesicular recycling endosome membranes were a core platform on which the critical early events of autophagosome formation occurred, including LC3-membrane conjugation to autophagic precursors. Here, we report...

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Share to Adaptor Proteins, Vesicular Transport
Share to Autophagosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Dynamin II

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Share to Microtubule-Associated Proteins

Share to Myopathies, Structural, Congenital

Source

Identifiers

PMID: 32315611
DOI: 10.1016/j.devcel.2020.03.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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