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Article

Downregulation of α-l-fucosidase 1 suppresses glioma progression by enhancing autophagy and inhibiting macrophage infiltration.

Cancer science - 1 Jul 2020

Xu Lixia, Li Zhenwei, Song Sirong, Chen Qian, Mo Lidong, Wang Chen, Fan Weijia, Yan Yan, Tong Xiaoguang, Yan Hua

Abstract excerpt

α-l-Fucosidase 1 (FUCA1), a lysosomal enzyme that catalyses the hydrolytic cleavage of the terminal fucose residue, has been reported to be involved in tumorigenesis. However, the clinical significance and biological roles of FUCA1 in glioma remain largely unknown. We analyzed FUCA1 expression according to data in Oncomine, The Cancer Genome Atlas, and Chinese Glioma Genome Atlas databases and further verified...

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Source

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Identifiers

PMID: 32314457
DOI: 10.1111/cas.14427
PMCID: PMC7385365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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