Article
Causal Association of Haptoglobin With Obesity in Mexican Children: A Mendelian Randomization Study.
The Journal of clinical endocrinology and metabolism - 1 Jul 2020
Vázquez-Moreno Miguel, Locia-Morales Daniel, Perez-Herrera Aleyda, Gomez-Diaz Rita A, Gonzalez-Dzib Roxana, Valdez-González Adriana L, Flores-Alfaro Eugenia, Corona-Salazar Perla, Suarez-Sanchez Fernando, Gomez-Zamudio Jaime, Valladares-Salgado Adan, Wacher-Rodarte Niels, Cruz Miguel, Meyre David
Abstract excerpt
CONTEXT: Little is known about the association between haptoglobin level and cardiometabolic traits. A previous genome-wide association study identified rs2000999 in the HP gene as the stronger genetic contributor to serum haptoglobin level in European populations. OBJECTIVE AND DESIGN: We investigated the association of HP rs2000999 with serum haptoglobin and childhood and adult obesity in up to 540/697 and...
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