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Caco-2 Cells for Measuring Intestinal Cholesterol Transport - Possibilities and Limitations

11 Apr 2020

Abstract excerpt

BACKGROUND: The human Caco-2 cell line is a common in vitro model of the intestinal epithelial barrier. As the intestine is a major interface in cholesterol turnover and represents a non-biliary pathway for cholesterol excretion, Caco-2 cells are also a valuable model for studying cholesterol homeostasis, including cholesterol uptake and efflux. Currently available protocols are, however, either sketchy or not...

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PMID: 32308567
DOI: 10.1186/s12575-020-00120-w

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