Article
TLmutation: Predicting the Effects of Mutations Using Transfer Learning.
The journal of physical chemistry. B - 14 May 2020
Shamsi Zahra, Chan Matthew, Shukla Diwakar
Abstract excerpt
A reccurring challenge in bioinformatics is predicting the phenotypic consequence of amino acid variation in proteins. With the recent advancements in sequencing techniques, sufficient genomic data has become available to train models that predict the evolutionary statistical energies, but there is still inadequate experimental data to directly predict functional effects. One approach to overcome this data...
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