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Article

Molecular and clinical features of myeloid neoplasms with somatic DDX41 mutations

19 Apr 2020

Abstract excerpt

We screened 47 subjects with DDX41 variants among 1529 subjects with myeloid neoplasms. The most common germline variants included Splice c.935 + 4A>T, p.T360Ifs*33, p.V152G, p.S217Ifs*4, p.R311* and p.R369*. Except for the p.R369*, no other variants have been previously reported. Clinical covariates of subjects with simple DDX41 somatic variants and germline/somatic biallelic variants are similar. The two-year...

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PMID: 32307695
DOI: 10.1111/bjh.16668

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