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Article

Identification of CTNNB1-PLAG1 gene rearrangement in a patient with pulmonary pleomorphic adenoma.

Virchows Archiv : an international journal of pathology - 1 Nov 2020

Asahina Miki, Hayashi Takuo, Takamochi Kazuya, Saito Tsuyoshi, Onagi Hiroko, Kishi Monami, Fukumura Yuki, Arakawa Atsushi, Suzuki Kenji, Yao Takashi

Abstract excerpt

Pulmonary pleomorphic adenoma (PA) is a rare salivary gland-type neoplasm, which predominantly occurs in the proximal airway. Rearrangement of the pleomorphic adenoma gene 1 (PLAG1) is the most frequent genetic event in PAs of salivary glands. However, whether pulmonary PA also harbors PLAG1 rearrangement has not been elucidated. Here, we present a case of pulmonary PA, located at the middle lobar bronchus, in a...

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PMID: 32307573
DOI: 10.1007/s00428-020-02810-y

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