Article
Association of hMSH5 C85T polymorphism with radiation sensitivity of testicular cell lines GC-1, GC-2, TM3, and TM4.
Andrology - 1 Sept 2020
Lin Mingyue, Guo Lihuang, Cheng Zhenbo, Huan Xisha, Huang Yue, Xu Keqian
Abstract excerpt
BACKGROUND: The hMSH5 C85T polymorphism, which encodes hMSH5 P29S, is associated with individual differences in spermatogenic abnormalities caused by ionizing radiation (IR), but the molecular mechanisms remain unclear. OBJECTIVES: This manuscript aims to explore the role of hMSH5 C85T polymorphism in IR-induced individual differences in spermatogenic abnormalities. MATERIAL AND METHODS: We transfected...
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