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Article

MutS homologue hMSH5: recombinational DSB repair and non-synonymous polymorphic variants.

PloS one - 1 Jan 2013

Wu Xiling, Xu Yang, Feng Katey, Tompkins Joshua D, Her Chengtao

Abstract excerpt

Double-strand breaks (DSBs) constitute the most deleterious form of DNA lesions that can lead to genome alterations and cell death, and the vast majority of DSBs arise pathologically in response to DNA damaging agents such as ionizing radiation (IR) and chemotherapeutic agents. Recent studies have implicated a role for the human MutS homologue hMSH5 in homologous recombination (HR)-mediated DSB repair and the DNA...

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Identifiers

PMID: 24023853
DOI: 10.1371/journal.pone.0073284
PMCID: PMC3762724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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