Article
Identification and validation of immunogenic potential of India specific HPV-16 variant constructs: In-silico &in-vivo insight to vaccine development.
Scientific reports - 28 Oct 2015
Kumar Anoop, Hussain Showket, Sharma Gagan, Mehrotra Ravi, Gissmann Lutz, Das Bhudev C, Bharadwaj Mausumi
Abstract excerpt
Cervical cancer is one of the most common gynecological cancers in the world but in India, it is the top most cancer among women. Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the most important risk factor. The sequence variation(s) in the most common HR-HPV i.e. HPV type 16 leads to altered biological functions with possible clinical significance in the different geographical...
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