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Mitochondrial dysfunction and alcohol-associated liver disease: a novel pathway and therapeutic target

3 Mar 2020

Abstract excerpt

In a recent study in signal transduction and targeted therapy , Zhou et al. provided novel experimental data on the role of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) in causing abnormalities in the structure and function of mitochondria of hepatocytes, leading to liver injury and alcohol-associated liver disease (ALD). 1

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PMID: 32296016
DOI: 10.1038/s41392-020-0128-8

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