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Article

DNA methylation in promoter regions of genes involved in the reproductive and metabolic function of children born to women with PCOS

14 Apr 2020

Abstract excerpt

Clinical and experimental evidences indicate that epigenetic modifications induced by the prenatal environment are related to metabolic and reproductive derangements in polycystic ovary syndrome (PCOS). Alterations in the leptin and adiponectin systems, androgen signalling and antimüllerian hormone (AMH) levels have been observed in PCOS women and in their offspring. Using a targeted Next-Generation Sequencing...

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PMID: 32283997
DOI: 10.1080/15592294.2020.1754674

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