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Mitofusin 1 is required for oocyte growth and communication with follicular somatic cells

12 Apr 2020

Abstract excerpt

Mitochondrial function, largely regulated by the dynamics of this organelle, is inextricably linked to the oocyte health. In comparison with most somatic cells, mitochondria in oocytes are smaller and rounder in appearance, suggesting limited fusion. The functional implications of this distinct morphology, and how changes in the mitochondrial shape translate to mitochondrial function in oogenesis is little...

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PMID: 32281181
DOI: 10.1096/fj.201901761r

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