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Article

Effect of mitophagy in oocytes and granulosa cells on oocyte quality†

20 Oct 2020

Abstract excerpt

Mitophagy is the process by which cells selectively remove supernumerary or damaged mitochondria through autophagy, and is crucial for mitochondrial homeostasis and cell survival. Mitochondria play vital roles in determining the developmental competence of oocytes. During the early stages of oogenesis, aberrant mitochondria can be removed by mitophagy. After oocyte formation, mitophagy is not actively initiated...

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PMID: 33079172
DOI: 10.1093/biolre/ioaa194

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