Article
CD10 and CD34 as markers in vascular malformations with PIK3CA and TEK mutations.
Human pathology - 1 May 2020
Moneghini Laura, Tosi Delfina, Graziani Daniela, Caretti Anna, Colletti Giacomo, Baraldini Vittoria, Cattaneo Elisa, Spaccini Luigina, Zocca Alfredo, Bulfamante Gaetano Pietro
Abstract excerpt
AIMS: Vascular malformations (vMs) encompass a wide range of diseases often associated with somatic or, more rarely, germinal genetic mutations. A mutation in the PIK3Ca/mTOR pathway is more often involved in various vMs. CD10 and CD34 are cellular markers that may play a role in mesenchymal differentiation and proliferation. The aim of our study was to find a possible link between the immunohistochemical...
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