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Exosomes Facilitate Transmission of Enterovirus A71 From Human Intestinal Epithelial Cells

7 Apr 2020

Abstract excerpt

BACKGROUND: Enterovirus A71 (EV-A71) has been noted for its tendency to lead to neurological manifestations in young children and infants. Although the alimentary tract has been identified as the primary replication site of this virus, how EV-A71 replicates in the gut and is transmitted to other organs remains unclear. METHODS: By using differentiated C2BBe1 cells as a model, we observed that intestinal...

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PMID: 32271384
DOI: 10.1093/infdis/jiaa174

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