Article
Trehalose metabolism confers developmental robustness and stability in Drosophila by regulating glucose homeostasis.
Communications biology - 7 Apr 2020
Matsushita Ryota, Nishimura Takashi
Abstract excerpt
Organisms have evolved molecular mechanisms to ensure consistent and invariant phenotypes in the face of environmental fluctuations. Developmental homeostasis is determined by two factors: robustness, which buffers against environmental variations; and developmental stability, which buffers against intrinsic random variations. However, our understanding of these noise-buffering mechanisms remains incomplete....
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