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Article

Role of tumor microenvironment in the regulation of PD‐L1: A novel role in resistance to cancer immunotherapy

2 Apr 2020

Abstract excerpt

Tumor evasion from the host immune system is a substantial strategy for tumor development and survival. The expression of many immune checkpoint proteins in cancer cells is a mechanism by which tumor cells escape from the immune system. Among the well-known immune checkpoints that can tremendously affect tumor development and cancer therapy are the programmed death-ligand-1/programmed death-1 (PD-L1/PD-1). To...

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PMID: 32239707
DOI: 10.1002/jcp.29671

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