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A Comparison of HLA Molecular Mismatch Methods to Determine HLA Immunogenicity

14 Feb 2018

Abstract excerpt

BACKGROUND: Antibody-mediated rejection is a major cause of premature graft loss in kidney transplantation. Multiple scoring systems are available to assess the HLA mismatch between donors and recipients at the molecular level; however, their correlation with the development of de novo donor-specific antibody (dnDSA) has not been compared in recipients on active immunosuppression. METHODS: HLA-DRβ1/3/4/5/DQα1β1...

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Share to Organ Transplantation Techniques and Outcomes
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PMID: 29443827
DOI: 10.1097/tp.0000000000002117

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