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Article

Association of polymorphisms in TNF-α, IL-1β, GSTM and GSTT genes with apical periodontitis: is there a link with herpesviral infection?

International endodontic journal - 1 Jul 2020

Jakovljevic A, Nikolic N, Carkic J, Beljic-Ivanovic K, Soldatovic I, Miletic M, Andric M, Milasin J

Abstract excerpt

AIM: To investigate the possible association between TNFα (-308 G/A) and IL-1β (-511 C/T) single nucleotide polymorphisms (SNPs) and GSTT and GSTM deletion polymorphisms and risk of apical periodontitis (AP) development, and determine the association of different genotypes with the presence of herpesviral infection in AP. METHODOLOGY: The study included 120 periapical lesions and 200 control samples. Gene...

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PMID: 32216135
DOI: 10.1111/iej.13298

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