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Germ cell-intrinsic effects of sex chromosomes on early oocyte differentiation in mice

26 Mar 2020

Abstract excerpt

A set of sex chromosomes is required for gametogenesis in both males and females, as represented by sex chromosome disorders causing agametic phenotypes. Although studies using model animals have investigated the functional requirement of sex chromosomes, involvement of these chromosomes in gametogenesis remains elusive. Here, we elicit a germ cell-intrinsic effect of sex chromosomes on oogenesis, using a novel...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
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PMID: 32214314
DOI: 10.1371/journal.pgen.1008676

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