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Article

Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.

Nature communications - 24 Mar 2020

Hollis Ben, Day Felix R, Busch Alexander S, Thompson Deborah J, Soares Ana Luiza G, Timmers Paul R H J, Kwong Alex, Easton Doug F, Joshi Peter K, Timpson Nicholas J, Ong Ken K, Perry John R B

Abstract excerpt

The timing of puberty is highly variable and is associated with long-term health outcomes. To date, understanding of the genetic control of puberty timing is based largely on studies in women. Here, we report a multi-trait genome-wide association study for male puberty timing with an effective sample size of 205,354 men. We find moderately strong genomic correlation in puberty timing between sexes (rg = 0.68) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32210231
DOI: 10.1038/s41467-020-14451-5
PMCID: PMC7093467

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