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Article

Alcohol-induced suppression of KDM6B dysregulates the mineralization potential in dental pulp stem cells

31 May 2016

Abstract excerpt

Epigenetic changes, such as alteration of DNA methylation patterns, have been proposed as a molecular mechanism underlying the effect of alcohol on the maintenance of adult stem cells. We have performed genome-wide gene expression microarray and DNA methylome analysis to identify molecular alterations via DNA methylation changes associated with exposure of human dental pulp stem cells (DPSCs) to ethanol (EtOH)....

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PMID: 27286573
DOI: 10.1016/j.scr.2016.05.021

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