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Article

NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo.

PLoS neglected tropical diseases - 1 Mar 2020

Colmant Agathe M G, Bielefeldt-Ohmann Helle, Vet Laura J, O'Brien Caitlin A, Bowen Richard A, Hartwig Airn E, Davis Steven, Piyasena Thisun B H, Habarugira Gervais, Harrison Jessica J, Hobson-Peters Jody, Hall Roy A

Abstract excerpt

Flaviviruses such as yellow fever, dengue or Zika viruses are responsible for significant human and veterinary diseases worldwide. These viruses contain an RNA genome, prone to mutations, which enhances their potential to emerge as pathogens. Bamaga virus (BgV) is a mosquito-borne flavivirus in the yellow fever virus group that we have previously shown to be host-restricted in vertebrates and horizontally...

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Identifiers

PMID: 32203536
DOI: 10.1371/journal.pntd.0008166
PMCID: PMC7089401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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