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Article

Bluetongue Virus NS4 Protein Is an Interferon Antagonist and a Determinant of Virus Virulence

24 Mar 2016

Abstract excerpt

UNLABELLED: Bluetongue virus (BTV) is the causative agent of bluetongue, a major infectious disease of ruminants with serious consequences to both animal health and the economy. The clinical outcome of BTV infection is highly variable and dependent on a variety of factors related to both the virus and the host. In this study, we show that the BTV nonstructural protein NS4 favors viral replication in sheep, the...

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PMID: 27009961
DOI: 10.1128/jvi.00422-16

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