Article
Factors predicting survival in chronic lymphocytic leukemia patients developing Richter syndrome transformation into Hodgkin lymphoma.
American journal of hematology - 1 Jun 2017
Mauro Francesca Romana, Galieni Piero, Tedeschi Alessandra, Laurenti Luca, Del Poeta Giovanni, Reda Gianluigi, Motta Marina, Gozzetti Alessandro, Murru Roberta, Caputo Maria Denise, Campanelli Melissa, Frustaci Anna Maria, Innocenti Idanna, Raponi Sara, Guarini Anna, Morabito Fortunato, Foà Robin, Gentile Massimo
Abstract excerpt
We hereby report the clinical and biologic features of 33 of 4680 (0.7%) patients with chronic lymphocytic leukemia (CLL), managed at 10 Italian centers, who developed Hodgkin lymphoma (HL), a rare variant of Richter syndrome. The median age at CLL and at HL diagnosis were 61 years (range 41-80) and 70 years (range 46-82), respectively, with a median interval from CLL to the diagnosis of HL of 90 months (range...
Topics
- Adult
- Aged
- Aged, 80 and over
- Antineoplastic Combined Chemotherapy Protocols
- Bleomycin
- Combined Modality Therapy
- Dacarbazine
- Doxorubicin
- Female