Article
Alcohol Drinking and Amyotrophic Lateral Sclerosis: An Instrumental Variable Causal Inference.
Annals of neurology - 1 Jul 2020
Yu Xinghao, Wang Ting, Chen Yiming, Shen Ziyuan, Gao Yixing, Xiao Lishun, Zheng Junnian, Zeng Ping
Abstract excerpt
Observational studies have shown alcohol drinking behaviors may be associated with the risk of amyotrophic lateral sclerosis (ALS), but contradictory findings have emerged, and whether such an association is causal is unclear. We here investigate the causal relationship between alcohol consumption and ALS. By leveraging instruments from large-scale genome-wide association studies, we performed a comprehensive...
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