Article
Plasma skeletal muscle myosin phenotypes identified by immunoblotting are associated with pulmonary embolism occurrence in young adults.
Thrombosis research - 1 May 2020
Deguchi Taichi K, Deguchi Hiroshi, Guo Zihan, Elias Darlene J, Griffin John H
Abstract excerpt
BACKGROUND: Purified skeletal muscle myosin (SkM) binds factor Xa and is procoagulant. The molecular forms of SkM in human plasma have not been characterized. METHOD: Human plasma SkM heavy chain (HC) isoforms of different molecular weights were detected by a newly developed immunoblotting protocol. In this pilot study, the distribution of SkM HC antigen isoforms in plasmas of healthy subjects and young adult...
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