Article
Comparison of monoclonal and polyclonal enzyme-linked immunoabsorbent (ELISA) assays for serum Lp(a) and differences in reactivities to Lp(a) phenotypes.
Journal of clinical laboratory analysis - 1 Jan 1995
Morikawa W, Iki R, Terano T, Funatsu A, Sugiuchi H, Uji Y, Okabe H
Abstract excerpt
We have prepared a monoclonal antibody to Lipoprotein(a)[Lp(a)] and have used it to develop an ELISA test for assaying Lp(a) in serum. The monoclonal antibody employed in the assay system reacts uniformly with S1, S2, S3 and B phenotypes of isoforms, and no cross-reaction with plasminogen at a co...
Topics
- Adult
- Animals
- Antibodies, Monoclonal
- Cross Reactions
- Enzyme-Linked Immunosorbent Assay
- Female
- Humans
- Lipoprotein(a)
- Male
- Mice
- Mice, Inbred BALB C
- Middle Aged
- Phenotype
- Plasminogen
- Reference Standards
- Reproducibility of Results