Article
Prevalence of the BRAF p.v600e variant in patients with colorectal cancer from Mexico and its estimated frequency in Latin American and Caribbean populations.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Jun 2020
Hernández-Sandoval Jesús Arturo, Gutiérrez-Angulo Melva, Magaña-Torres María Teresa, Alvizo-Rodríguez Carlos Rogelio, Ramírez-Plascencia Helen Haydee Fernanda, Flores-López Beatriz Armida, Valenzuela-Pérez Jesús Alonso, Peregrina-Sandoval Jorge, Moreno-Ortiz José Miguel, Domínguez-Valentín Mev, Ayala-Madrigal María de la Luz
Abstract excerpt
This study aimed to investigate the frequency of the somatic BRAF p.V600E in patients with colorectal cancer (CRC) in Mexico and compare it with those estimated for Latin American and Caribbean populations. One hundred and one patients with CRC with AJCC stages ranging I-IV from Western Mexico were included, out of which 55% were male and 61% had AJCC stage III-IV, with a mean age of 60 years. PCR-Sanger...
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