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Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells

13 Mar 2020

Abstract excerpt

Human pluripotent stem cells (hPSCs) can provide unlimited supply for mesenchymal stem cells (MSCs) and adipocytes that can be used for therapeutic applications. Here we developed a simple and highly efficient all-trans-retinoic acid (RA)-based method for generating an off-the-shelf and scalable number of human pluripotent stem cell (hPSC)-derived MSCs with enhanced adipogenic potential. We showed that short...

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PMID: 32183164
DOI: 10.3390/cells9030710

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