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Human and mouse adipose-derived cells support feeder-independent induction of pluripotent stem cells

3 Feb 2010

Abstract excerpt

Although adipose tissue is an expandable and readily attainable source of proliferating, multipotent stem cells, its potential for use in regenerative medicine has not been extensively explored. Here we report that adult human and mouse adipose-derived stem cells can be reprogrammed to induced pluripotent stem (iPS) cells with substantially higher efficiencies than those reported for human and mouse fibroblasts....

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PMID: 20133714
DOI: 10.1073/pnas.0910172106

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